Africanus read a 'messiah will be killed and disappear' and incorporated the Hebrew of Daniel 9:26 into his chronology unlike Eusebius and others who built a model around the disappearance of the unction.Now, in Greek, it happens that holm-tree and saw asunder, and rend and mastich-tree sound alike; but in Hebrew they are quite distinct. But all the books of the Old Testament have been translated from Hebrew into Greek. Moreover, how is it that they who were captives among the Chaldæans, lost and won at play, thrown out unburied on the streets, as was prophesied of the former captivity, their sons torn from them to be eunuchs, and their daughters to be concubines, as had been prophesied; how is it that such could pass sentence of death, and that on the wife of their king Joakim, whom the king of the Babylonians had made partner of his throne? Then if it was not this Joakim, but some other from the common people, whence had a captive such a mansion and spacious garden? But a more fatal objection is, that this section, along with the other two at the end of it, is not contained in the Daniel received among the Jews. And add that, among all the many prophets who had been before, there is no one who has quoted from another word for word. For they had no need to go a-begging for words, since their own were true; but this one, in rebuking one of those men, quotes the words of the Lord: The innocent and righteous shall you not slay. From all this I infer that this section is a later addition. Moreover, the style is different. I have struck the blow; do you give the echo; answer, and instruct me. Salute all my masters. The learned all salute you. With all my heart I pray for your and your circle's health.
So the order of interpretations goes:
c. 160 - 190 CE Against the Jews (original translated by Tertullian loosely into Latin) makes Jesus's crucifixion = Daniel 9:26
221 CE Africanus who clearly read 'messiah' not unction and worked out a chronology where the seventy weeks ends at the crucifixion (undoubtedly jumbling the order of 'events' as they appear in Daniel as we see in Against the Jews)
320 CE Eusebius who completely avoids the reading 'messiah' and used the Greek translation to build a historical model around the disappearance of the unction.
Christian exegesis of the Seventy Weeks prophesy is clearly moving away from an explicit identification of the Passion with Daniel 9:26.